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Frequency of genetic mutations causing resistance to Rifampicin and Isoniazid in Mycobacterium tuberculosis from clinical specimens using molecular line probe assay in Kenya

*Mutua Daniel, Ngaira Jane, Mukiri Nellie, Kamau George, Kissinger Henry, and Limo Jacqueline

 

Drug resistance in Mycobacterium tuberculosis is as a result of genetic mutation occurring spontaneously in highly conserved regions of Mycobacterium genome. This cross-sectional study was to evaluate frequencies of genetic mutations conferring resistance to rifampicin and Isoniazid using molecular line probe assay (LPA). A total of 429 sputum specimens were selected randomly from samples processed at the National Tuberculosis Reference laboratory, Kenya between 2016-2017.

 

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Comparison of Anthropometric and Somatotype characteristics of amateur and professional soccer goalkeepers in Trabzon

Prof. Dr. Vedat Ayan, Yalçın İnan, and Prof. Dr. Selami Yüksek

 

The purpose of this study was to determine and compare the somatotype differences between the junior goalkeepers playing for the amateur and professional soccer teams in the U-13 League of Trabzon. Sixty volunteer goalkeepers, including 30 professional and 30 amateur players from professional and amateur teams in the city of Trabzon, participated in this study. For somatotype calculations, ten anthropometric variables including height, mass, selected diameters, girths and skinfold thickness were measured.

 

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CURRENT ISSUES

 

Test performance and correlates of bacterial vaginosis among women in Western Kenya

Rosemary A. Okuku, Christine Bii, Ernest Makohka, Joseph Gikunji, and Musa Otieno Ngayo

 

Bacterial vaginosis (BV), a common lower genital tract infection among women, is associated with adverse birth outcomes and increased risk of HIV/STD. BV, is by far most common and yet under-diagnosed among women in sub-Saharan Africa. With poor laboratory infrastructure and lack of skilled personnel, evaluating BV associated factors and point-of-care diagnostic tests are important for prevention and management in Kenya. Vaginal swabs from 227 women (18 years or older) attending Kakamega County Referral Hospital (KCRH) in Western Kenya were tested for BV using Quickvue Advance pH and Amines test, Amsel’s and Nugent’s criteria as the gold standard. Structured interviews gathered information on factors associated with BV among this population.

 

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