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Prime Journal of Microbiology Research

 Prime Journal of Microbiology Research | ISSN: 2251-127X

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Prime Journal of Microbiology Research

ISSN: 2251-127X. Volume 2, Issue 3, pp. 126-130

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Prevalence and antimicrobial susceptibility of uropathogen among the patients in a tertiary health institution in Ado Ekiti, Nigeria


Daniyan SY and Ojo BA


Department of Microbiology, Federal University of Technology Minna, Nigeria.


Accepted 16th April, 2012



This study was carried out to determine the prevalence and antibiotic susceptibility of bacteria associated with urinary tract infection (UTI) of patient in one of the tertiary health institution, Nigeria. Clean-catch midstream urine was collected from 130 patients (57 males and 73 females) and culture on CLED agar plates. Isolates were identified and antibiotic susceptibility testing was performed. Results: The prevalence of urinary tract infection was significantly higher in females (68.5%) compared to males (45.6%). Seventy six (58.46%) were urine culture positive for microbial pathogens with 82 microbial isolates. In general 55 (67.07%) isolates were gram negative and 27 (32.93%) isolates were gram positive. Escherichia coli 26 (31.7%) has the highest percentage follow by Staphylococcus aureus 18(21.9%) and Klebsiella spp 10 (12.2%). The in vitro antibiotic susceptibility pattern of the isolates show high resistance to common antibiotic used. Nitrofurantoin has the highest antibiotic activity with total average percentage of 63.9% in gram negative isolates followed by Ofloxacin 34.4%, while total average percentage of 38.2% isolates were susceptible to Chloramphenical and 22.5% to Tetracycline, but highest resistance were shown in Amoxicillin Cloxacillin, Augumentin, Cotrimoxazole and Gentamicin. Conclusion: A 58.46% prevalence of UTIs was found. This problem remarks significance of performing antimicrobial susceptibility testing before empiric antibiotic therapy.


Keywords: Prevalence, antimicrobial susceptibility, uropathogen, catheter, Nigeria.

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Daniyan SY

Ojo BA



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